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J G Mabley Selected Research

Inflammation (Inflammations)

1/2003Inosine reduces inflammation and improves survival in a murine model of colitis.
11/2001Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase.
10/2001Inosine reduces systemic inflammation and improves survival in septic shock induced by cecal ligation and puncture.
1/2000Inosine inhibits inflammatory cytokine production by a posttranscriptional mechanism and protects against endotoxin-induced shock.

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J G Mabley Research Topics

Disease

4Inflammation (Inflammations)
01/2003 - 01/2000
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
06/2002 - 06/2001
2Colitis
01/2003 - 11/2001
2Hyperglycemia
03/2002 - 01/2001
2Necrosis
06/2001 - 08/2000
1Bone Resorption
12/2003
1Periodontitis
12/2003
1Hemorrhage
01/2003
1Autoimmune Diseases (Autoimmune Disease)
03/2002
1Cardiotoxicity
03/2002
1Heart Failure
03/2002
1Stroke (Strokes)
11/2001
1Endotoxemia
11/2001
1Experimental Diabetes Mellitus
11/2001
1Arthritis (Polyarthritis)
11/2001
1Peritonitis
11/2001
1Uveitis
11/2001
1Sepsis (Septicemia)
10/2001
1Septic Shock (Toxic Shock Syndrome)
10/2001
1Hemorrhagic Shock
08/2000
1Shock
01/2000
1Ischemia
01/2000

Drug/Important Bio-Agent (IBA)

4CytokinesIBA
01/2003 - 01/2000
3EnzymesIBA
12/2003 - 08/2000
3Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2003 - 06/2001
3Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
12/2003 - 08/2000
3InosineFDA Link
01/2003 - 01/2000
3Oxidants (Oxidizing Agents)IBA
11/2001 - 08/2000
2N- (oxo- 5,6- dihydrophenanthridin- 2- yl)- N,N- dimethylacetamide hydrochlorideIBA
12/2003 - 11/2001
2Dextran SulfateIBA
01/2003 - 11/2001
2ChemokinesIBA
01/2003 - 06/2002
2Streptozocin (Streptozotocin)FDA Link
03/2002 - 01/2001
2EndotoxinsIBA
11/2001 - 01/2000
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2001 - 06/2001
2Poly(ADP-ribose) Polymerase InhibitorsIBA
11/2001 - 01/2001
1Evans Blue (Blue, Evans)FDA Link
12/2003
1Proteins (Proteins, Gene)FDA Link
06/2002
1Transcription Factors (Transcription Factor)IBA
06/2002
1NicotineFDA Link
03/2002
1Insulin (Novolin)FDA Link
03/2002
1AnthracyclinesIBA
03/2002
1Anti-Bacterial Agents (Antibiotics)IBA
03/2002
1Doxorubicin (Adriamycin)FDA LinkGeneric
03/2002
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2001
1NitritesIBA
11/2001
1NitrogenIBA
11/2001
1Oxygen (Dioxygen)IBA
11/2001
1Free RadicalsIBA
11/2001
1NitratesIBA
11/2001
1InterleukinsIBA
06/2001
1Interferon-gamma (Interferon, gamma)IBA
06/2001
13-nitrotyrosineIBA
06/2001
1Superoxides (Superoxide)IBA
06/2001
1Peroxynitrous Acid (Peroxynitrite)IBA
06/2001
1DNA (Deoxyribonucleic Acid)IBA
01/2001
1PurinesIBA
01/2000

Therapy/Procedure

2Therapeutics
12/2003 - 01/2003
2Ligation
12/2003 - 10/2001
1Punctures
10/2001
1Resuscitation
08/2000